Brianna Rapini graduated from the University of Texas-Austin with a bachelor of science in biology. She received a master’s degree in educational administration from Sam Houston State University and a master’s degree in biological sciences from Clemson University. Brianna and her sister (Sarina Peterson) created the science YouTube Channel Amoeba Sisters, which specializes in teaching biology concepts by using illustrated cartoons. As of January 2024, the channel has grown to over 1.9 million subscribers with a cumulative view count of over 200 million, and their online community has translated video subtitles in over 22 languages. Brianna writes the content and does the voicing for the Amoeba Sisters videos. She also designs supplemental resources that complement the videos. Prior to working full-time on Amoeba Sisters, Brianna worked in three different public school districts for a total of twelve years. Her experience has included being a classroom AP / on-level biology teacher, instructional technology specialist, campus science specialist, and district science coordinator.